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Mechanistically, ferroptosis is mediated by the generation of toxic oxidized lipids, including 4-hydroxynonenal [6], as a result of lipid peroxidation [7]

Planimetry measurements provided quantitative evidence of these clinical observations

Conversely, interventions that restore robust circadian oscillations through melatonin, timed light exposure, or meal scheduling, show promise in improving health outcomes in older adults

Signs of a secondary bacterial infection also require attention

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