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Malignant intercostal psammomatous melanotic schwannoma in a patient with Carney complex
In the phase 2 clinical trial (Jastreboff et al., New England Journal of Medicine , 2023), retatrutide was administered as a once-weekly subcutaneous injection, with doses escalated gradually over time a regimen that reflects the trial protocol
Another trial, SOUL (NCT03914326), has now been initiated to overcome the shortcomings of PIONEER 6 with a primary endpoint focused at proving CV superiority vs placebo
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