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Toxicol Mech Methods
Authors have reported mild and temporary skin reactions at the injection site, such as redness, itching, or swelling
PLGA NPs have demonstrated minimal cytotoxic effects at concentrations up to 100 g/ml in both neuronal and glial cell cultures, and in vivo studies suggest lower accumulation in brain tissue and faster systemic clearance compared to metallic analogues [180]
Genetics, gut microbiome composition, baseline GI health, concurrent medications, and individual amylin receptor sensitivity all contribute to this variation
IV Therapy vs
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