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When oral peptide programs advanced into clinical development, they encountered one or more insurmountable obstacles: extreme inter- and intra-subject variability, inability to meet bioequivalence criteria, unacceptable local gastrointestinal class effects at effective doses, or prohibitive cost of goods due to dose escalation (Karsdal et al., 2010

During this adjustment period, increased fermentation of fibers and the natural turnover of microbial communities may lead to temporary gas

Ferrero RL, Cussac V, Courcoux P, Labigne A (1992) Construction of isogenic urease-negative mutants of Helicobacter pylori by allelic exchange

Curcumin is a golden child of the supplement industry, and for a good reason

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