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You may also need to restart your medication from the lowest dose, losing both time and progress

Change from baseline in A1C was the primary efficacy end point in all LEAD trials

In ATTAIN-1, the familiar cluster appeared again: nausea, diarrhoea, constipation, vomiting, indigestion, and abdominal pain, mostly mild to moderate and concentrated during the weeks when the dose was being stepped up

It is possible that the increased physical activity that is made possible when people lose substantial amounts of weight could result in the appearance of joint symptoms that were previously masked by inactivity

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