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For example, research published in JAMA Network Open found that between 2018 and 2023, spending on GLP-1s increased by a whopping 500%, from $13.7 billion to $71.7 billion
14 A calculator to assess cardiovascular disease risk in people with type 2 diabetes is available here: Clinical scenarios where empagliflozin or dulaglutide are recommended, but not funded The recently released type 2 diabetes management guidelines developed by the New Zealand Society for the Study of Diabetes (NZSSD), and supported by the Ministry of Health, state that while the Special Authority criteria for empagliflozin and GLP-1 receptor agonists ensure access for those at high risk of cardiovascular and renal disease, the funding restriction is not fully consistent with best practice
It promotes angiogenesis through VEGF pathway activation, modulates nitric oxide production, and produces cytoprotective effects in connective tissue, vascular endothelium, and gastrointestinal epithelium
As healthcare systems prioritize chronic disease management, GLP-1 receptor agonists are positioned to remain a critical component of treatment protocols