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Other Pituitary Hormones No clinically significant changes in the levels of other pituitary hormones, including thyroid-stimulating hormone (TSH), luteinizing hormone (LH), adrenocorticotropic hormone (ACTH) and prolactin, were observed in subjects receiving tesamorelin in Phase 3 clinical trials

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This diversion leads to the accumulation of sorbitol and fructose within cells, increasing intracellular osmolarity and causing osmotic stress

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