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Originally developed for glycemic control, semaglutide promotes glucose-dependent insulin secretion, suppresses glucagon release, delays gastric emptying, and, most importantly for MASH, produces significant weight loss through the hypothalamic regulation of appetite and satiety

Combining tirzepatide with other weight loss medications like phentermine is an option some providers use to accelerate results, though this should only be done under medical supervision

To prevent this, a high protein diet for Wegovy is mandatory

mcg) that the calculator expects

However, further research is needed to explore long-term effects and optimise treatment strategies