3) REDEFINE-1 (NEJM 2024, n=3417, 68 weeks) CagriSema (cagrilintide 2.4 + semaglutide 2.4) 22.7% weight (ozempic 2.4 16.1%, cagrilintide 2.4 mono 11.8%, placebo 2.3%)
Lyophilized tirzepatide has no water present, which means most degradation pathways are dramatically slowed
Preliminary data suggest that tirzepatide, by improving weight and metabolic status, may enhance patient adherence to CPAP therapy and amplify overall therapeutic outcomes (53, 54)
Faster recovery (in weeks to months) is reported in patients treated with high doses of oral glucocorticoids for less than 1 month.19 HPAA recovery could take up to 6 to 12 months in patients treated with glucocorticoids for more than 12 months
I could not be more excited for my patients, their families, and the MASH community." Michael Betel, President and Founder of the Fatty Liver Alliance: "Our community has long awaited an approved treatment option for MASH