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Unlike some products on the market, these supplements work without harsh stimulants or side effects , so they can be taken safely over the long term
However, it is still an investigational medicine, and important questions remain about its long-term safety, durability of weight loss and effectiveness across different patient groups
On the other hand, IGF-IR may trigger EMT via STAT3, FAK, and NF-kB [67, 68]
But as scientists and drug developers isolate the mechanisms behind their anti-cancer, anti-dementia, and anti-inflammatory effects, we might get specially tailored drugs for cancer, dementia, and inflammation
These studies looked at GLP1-RAs in those with obesity and other comorbidities, without T2D, at weight loss doses
