B12 supports red blood cell production and energy metabolism, which matters during caloric restriction when fatigue commonly derails adherence
Targeted Health Wins: There is promising (but early) research linking it to improvements in fatty liver markers, insulin sensitivity, and circulation in leg arteries (Healthline

While glutathione supplements are broadly suitable for almost anyone who wants to increase their body's capacity to combat oxidative stress, they can best serve individuals who wish to prevent, delay, or alleviate specific chronic health conditions associated with glutathione depletion:15 Neurodegenerative disorders such as Alzheimer's and Parkinson's Respiratory diseases like asthma and COPD Cardiovascular diseases like hypertension and high cholesterol Age-related diseases like cataracts, macular degeneration, and hearing impairment Immune diseases like HIV and AIDS Liver disease Cystic fibrosis Additionally, because the goal is to reduce oxidative stress, people who are regularly exposed to ROS-generating compounds (e.g., smoke, alcohol, and sunlight)23 might consider adding glutathione to their supplement rotation, at least to help counter the effects of oxidative stressors

Additionally, B12 is essential for the conversion of homocysteine to methionine, preventing the accumulation of homocysteine, which is associated with cardiovascular risk
November 9, 2006