Mechanism Retatrutide is a triple agonist, targeting GIP, GLP-1, and glucagon receptors
The more muscular and lean you are, the higher the proportion of weight lost that is likely to be muscle
Here is how to think about it clearly: Choose tirzepatide if: Maximum weight loss is your priority, you have insulin resistance or a high BMI, you previously plateaued on semaglutide, or your insurance covers Zepbound or Mounjaro
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