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Glutathione levels also are lower and oxidative stress is higher in conditions associated with mitochondrial dysfunction, including ageing, HIV infection, diabetes, neurodegenerative disorders, cardiovascular disorders, neurometabolic diseases, cancer, obesity and other conditions

The general consensus is that any increased risk of retinopathy with GLP-1 RA treatment is likely to be related to the abrupt improvement in glycemic control [108], a phenomenon similar to that reported for other neuropathological complications [109]

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