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Available: Badawy, A.A., Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects, International Journal of Tryptophan Research

Aguillard, A

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In a 2026 editorial commentary published in Cureus , citing findings from the STEP 4 and SURMOUNT 4 clinical trials, the author described how stopping GLP-1 medication may unmask counter-regulatory hunger signals including potential changes in ghrelin activity that had been suppressed while the medication was active (Quimbayo-Cifuentes, 2026)

Conclusions Lack of consideration of MNTI in the differential diagnosis can lead to misdiagnosis and undue exposure to cytotoxic therapies