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The objective of this review is to critically assess the current evidence surrounding their mechanisms of action, clinical indications, efficacy, and safety profiles, with particular emphasis on regulatory and translational considerations

Bidirectional Communication Bidirectional communication manifests in multiple experimental paradigms: From brain to gut: Selye-type stress leading to gastroduodenal ulcers was counteracted by BPC-157, which modulated hypothalamic-pituitary-adrenal (HPA) axis function and vagal signaling

Molecular interactions enhance the combination further

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