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Interestingly by activation of the hexosamine pathway the glucose-mediated induction of lipogenic enzymes, glycerophosphate dehydrogenase (GPDH), fatty acid synthase (FAS) and acetyl-CoA carboxylase, was stimulated in liver and adipocytes(Fig 8)

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Dr Perna has received honoraria from Novo Nordisk

However, it has also been shown that consuming L-carnitine with food, specifically carbohydrates facilitates glycogen sparring during exercise

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