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First, the issue of intratumoral heterogeneity as well as tumor evolution is still a big challenge, underscoring the requirement for longitudinal multi-omics profiling and analysis to elucidate dynamic resistance mechanism (326)
They measured subjective sleep quality more than objective sleep quality They subjectively estimated tiredness Sleep structure was not fully characterized by polysomnography in all studies Data analysis suggested some observed changes were due to issues with the placebo group What is promising about these findings is that statistically significant effects were found in such small sample sizes
Daily urogenital review is recommended during the acute phase with the aim to reduce pain and prevent scarring [12]
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According to the findings, targeted therapy against oxidative stress administered in combination with antibiotics may serve as a promising strategy for preventing or delaying the gastric mucosal diseases caused by HP infection in the future (Singh et al., 2019)
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