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Acknowledgements The work of the authors cited in this review was partially supported by the Institut National de la Sant et de la Recherche Mdicale (INSERM), the Conseil Rgional de Bourgogne, and the Universit de Bourgogne

ROS can react with DNA and cause damage to purines and pyrimidines [6], resulting in the formation of 8-Hydroxy-deoxyguanosine (8-OHdG) [7]

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Neurohormonal Activation Pathways Neurohormonal pathways are key in how the body reacts to anemia