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The FDA has identified it as a Category 2 compound with safety concerns for compounding
A meta-analysis examining calorie-restricted subjects found that those supplementing with creatine maintained up to 60% more lean mass than non-supplemented controls over 8 weeks
The timing varies for each person
Its a sign that tirzepatide's powerful appetite-suppressing and glucose-regulating effects are creating a caloric deficit significant enough to trigger this fundamental metabolic change
By weeks 48, most patients report measurable weight loss ranging from 37 pounds, assuming consistent adherence and no major diet changes
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