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Consistent with the transcriptomic findings, proteomic analysis of liver from Gclc KO mice revealed that most significantly elevated proteins in Gclc KO liver were encoded by NRF2 target genes, including the canonical NRF2 target NQO1 (NAD(P)H Quinone Dehydrogenase 1) (Fig

In addition, confirming the efficacy of GSH treatment, a reduction in malondialdehyde, a marker of hepatic cell damage, was detected

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El uso de dosis altas de glutatin y la administracin intravenosa no estn regulados en muchos pases y pueden tener efectos a largo plazo desconocidos