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Selection criteria for the eta-analysis Inclusion criteria were studies (1) including healthy participants, (2) utilising 1 H-MRS to measure GSH levels in specified brain regions, (3) giving mean and SD for each group, (4) patients with depression only and not bipolar affective disorder in accordance with criteria specified in the Diagnostic and Statistical Manual for Mental Disorders (DSM) or the International Classification of Diseases (ICD-11), (5) information provided on sex of patients

The NGF/TrkA pathway participates in the induction of antioxidant responses in both the CNS and non-neural tissues (Sampath et al., 1994

REW - NCT06363383) [111, 112]

The two pathways are complementary, not redundant

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