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It is evident that the gut microbiota profoundly influences overall physiology and pathophysiology, as these microorganisms interact with nearly every organ in the body

Peer review Peer review information Nature Metabolism thanks Florian Greten, Luisa Iommarini and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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Retrieved 3 August 2010

Consistently, the GPx3 levels were reported to be down-regulated in aggressive inflammatory breast cancer (IBC) carcinoma tissues compared to non-IBC tissues, and this down-regulation was associated with hypermethylation of the GPx3 promoter [103]