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and melatonin preconditioning enhances ERC efficacy via antioxidant protection, significantly lowering both the disease activity index and tissue damage scores ( In the treatment of type 1 diabetes mellitus (T1DM), (Malik et al., 2018) confirmed that intravenous infusion of MenSCs results in targeted migration to the injured pancreas

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However, the decreased HDL cholesterol and apoA1 concentrations induced by modified fasting are contradictory to that reported in previous studies [38, 40] which showed that these parameters increased during the zero-calorie fasting period