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Unexpected results, lack of expected effects, or unusual adverse reactions warrant quality investigation

Any time someone in the limelight loses weight, the masses must know how they did it

Some studies report that even IV GSH may not increase epithelial lining fluid

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In the SURMOUNT-1 trial, tirzepatide showed significant weight loss results in adults without diabetes over 72 weeks (15-21% body weight reduction, depending on dose), while orlistat typically produces more modest results (approximately 3-5% additional weight loss beyond placebo at 1 year)