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Ca 2+ is a master regulator of eryptosis, mediating the Gardos effect-associated RBC dehydration and reduction of cell volume (cell shrinkage), calpain activation-mediated cytoskeleton remodeling (membrane blebbing), and PS externalization, which are major hallmarks of eryptosis

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Nausea is one of the most commonly reported side effects associated with injectable weight loss medications, particularly those in the glucagon-like peptide-1 (GLP-1) receptor agonist class