Higher doses can stall the very same process, or tip into outright toxicity over longer exposures, where free copper drifting loose from the complex starts driving oxidative damage
If solubility is difficult, a small amount of dilute acetic acid (e.g., 0.1%) is commonly used in peptide labs to aid dissolution
Having enough B12 is important for the babys growth and health
Brain Behav Immun 55:8292 Shan Y, Tan S, Lin Y, Liao S, Zhang B, Chen X, Wang J, Deng Z, Zeng Q, Zhang L, Wang Y, Hu XQ, Qiu W, Peng L, Lu ZQ (2019) The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke
The good news is that in general a) the concurrent use of clozapine with these medicines enhances outcomes, and b) they do not seem to cause significant side effects issues