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Research has demonstrated its involvement in wound healing through enhanced collagen and decorin gene expression [1] , activation of tissue remodeling pathways [2] , and regulation of genes associated with antioxidant defense and anti-inflammatory responses [3] [4]

Warfarin has high permeability and high/low solubility properties and is completely absorbed after oral administration, with a peak concentration occurring after 26 h [21, 22]

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After 1 h with constant vigorous shaking, cells were pulled down by centrifugation at 5000 rpm at 4 C for 10 min