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The methylation status of the PGC-1 promoter is closely linked to its expression and mitochondrial function, highlighting the role of methylation in regulating mitochondrial biosynthetic gene expression [253]
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It helps the body quickly replenish energy during very brief, intense physical efforts, such as lifting a heavy load, sprinting, or throwing
It is possible that the LKB1/AMPK/ACC pathway is activated by direct redox modulation of cellular proteins since activation of AMPK pathway has been directly linked to cellular redox status and hydrogen peroxide 49
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