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JAMA 2021
Refer Table 1 for a summarized tabulation of the dual role of LC in human health
Published safety and tolerability findings Published clinical studies on Tirzepatide indicate that the most commonly reported adverse events are gastrointestinal, especially nausea, diarrhoea, decreased appetite, vomiting and constipation
This does not invalidate the data, but it means the evidence base is narrower than the publication volume implies
Individuals can reduce or change metabolic demands by altering activity, behavior, physiology and metabolic pathways 12,25
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