[#8/8] avoid enoxaparin if an LP may be needed Consider adjusting the DVT prophylaxis strategy based on the likelihood of requiring a lumbar puncture: Moderate likelihood that LP will be needed: hold DVT prophylaxis initially
In some cases, recovery might take longer than expected
An initial analysis of the FDA adverse event reporting system (FAERS) data demonstrated no consistent trends in DKA with SGLT2i use over time [39], however an alternative cohort study of 50,220 individuals with type 2 diabetes showed the highest risk of DKA shortly after SGLT2i initiation, which subsequently reduced with time [40]
doi: 10.1111/febs.16638 63 HuynhTVDavisAAUlrichJDHoltzmanDM
Pros of GLP-1s: Non-surgical option Can lead to 1520% body weight loss in clinical trials May improve blood sugar, cholesterol, and inflammation Weekly injections, often self-administered Cons of GLP-1s: Real-world weight loss may be lower than clinical trials (510%) Side effects include nausea, vomiting, fatigue, and gastroparesis High cost and limited insurance coverage Weight may return if medication is stopped What is weight loss surgery