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Antioxidants are biological substances that act to neutralise and get rid of harmful ROS (Reactive Oxygen Species) and other free radicals
Subjects are injected intravenously with 51 Cr-EDTA solution, then 6-mL blood samples are drawn from the opposite arm at 2, 3, and 4 h
Selenium and GPx-1 overexpression protect mammalian cells against UV-induced DNA damage
Most of the GSH (8085%) is stored in the cytosol, 1015% in the mitochondria (with an equal concentration between matrix and cytosol, thus requiring specific transport systems) and a small part in the endoplasmic reticulum (ER) (1, 6, 7)
The finding established that the GSH redox cycle is the primary intracellular antioxidant defence system in endothelial cells against peroxide-mediated oxidative stress, and remains a foundational reference for endothelial oxidative stress research using GSH manipulation
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