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Studies of liver repopulation using the dipeptidyl peptidase IV-deficient rat and other rodent recipients: cell size and structure relationships regulate capacity for increased transplanted hepatocyte mass in the liver lobule

When combining these agents, patients may experience additive gastrointestinal effects, though clinical trial data suggest the combination is generally well-tolerated when appropriate dose titration strategies are employed

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These findings indicate that hepatic toxicity associated with anabolicandrogenic steroid use can be severe and, in some cases, life-threatening (75)