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This minimum requirement becomes the de facto standard

doi: 10.1016/j.ebiom.2019.09.002 74 GuoMChenQHuangYWuQZengYTanXet al

Zhang, Z., & Wang, C

Moreover, improvements in the injection instruments like the prefilled pens and autoinjectors have facilitated the administration process and increased the patient's comfort, thus the adherence rates have been uplifted

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