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Environmental pollutants, sun exposure, poor diet, chronic stress, smoking, and lack of sleep all contribute to oxidative stress, speeding up skin damage and aging

The review maps engineering solutions to tissue-specific delivery challenges, critically appraises evidence across primary musculoskeletal indications, and identifies translational bottlenecks separating preclinical claims from clinical reality

It promotes collagen production, maintains the skins elasticity, and protects it from environmental pollutants, keeping the skin soft, smooth, and healthy

Di Loreto C, La Marra F, Mazzon G, Belgrano E, Trombetta C, Cauci S