In the case of GLP-1s, their relatively mild side effect profile compared to their efficacy is one of the biggest selling points
But these drugs, such as Ozempic, Wegovy, and Trulicity, aren't just working their magic on your waistline
So, it is with any skin condition
Importantly, initiation of GLP-1RA may decrease levothyroxine dose requirements in patients with hypothyroidism through weight loss, enhance levothyroxine absorption due to delayed gastrointestinal (GI) transit, and have direct effects on the hypothalamic-pituitary-thyroid axis [23,24,25,26,27,28,29], potentially increasing the risk of thyroid hormone over-replacement (i.e., iatrogenic hyperthyroidism)
Some patients report that administering their GLP-1 injection in the evening, particularly after dinner, may help them manage early gastrointestinal side effects such as nausea, as they can sleep through the initial hours after injection