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OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis
The cost Peptide-based weight loss drugs are expensive, with an average list price of $1,000-$1,350 per month
The Arg3 substitution and N-terminal 13-residue extension in IGF-1 LR3 reduce IGFBP affinity by approximately 1,000-fold, preventing this sequestration
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