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Many patients experience uncomfortable side effects such as persistent nausea, vomiting, and diarrhea, which can severely disrupt daily life
Headaches occasionally occur, particularly during initial use periods
The World Health Organization (WHO) defines both overweight and obesity as abnormal or excessive fat accumulation that presents a risk to health
However, translation of these findings to adult human obesity remains constrained by fundamental physiological differences, including limited brown adipose tissue mass and reduced thermogenic capacity
EFSA Journal, 16(4), e05239
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