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When looking at weight loss, 9% of patients achieved 15% weight loss with semaglutide 1 mg once weekly compared with 40% of those receiving the 15 mg once-weekly dose of tirzepatide

Consult your healthcare provider before making any treatment decisions

However, thanks to the present results, and the SOUL cardiovascular outcomes trial of oral semaglutide confirming cardiovascular benefits in people with type 2 diabetes and CVD (McGuire et al, 2025), we now have more evidence-based drug options for the people we support