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The Fat Transporter Not Just a Fat Burner
When oxidative throughput remains sustained while substrate availability declines, discrete rate-limiting biochemical nodes may emerge [76, 77]
GLP-1 functions to delay gastric emptying, stimulate insulin secretion and mediate satiety in the central nervous system (CNS), all actions that are beneficial to individuals with obesity and type 2 diabetes
Lancet 377:13411352 Allison DB, Gadde KM, Garvey WT, Peterson CA, Schwiers ML, Najarian T, Tam PY, Troupin B, Day WW (2012) Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP)
Because retatrutide is unlicensed, it may only be used lawfully in the UK within an authorised clinical trial (as an Investigational Medicinal Product, or IMP) or under specific MHRA-regulated frameworks for unlicensed medicines
