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At the time of assay, the growth medium was replaced with HBSS, supplemented with 10 mM HEPES and 0.1% (w/v) ovalbumin and incubated at room temperature for 30 min

2020;5(7):e134838

Hyperpigmentation: 4% niacinamide reduces melasma severity, and 5% formulations show tone improvement when paired with antioxidants and tranexamic acid

doi: 10.1007/S11745-000-0607-X 86 ShahidSKKharitonovSAWilsonNMBushABarnesPJ

The serotonin system is the target of many therapeutic drugs, including SSRIs, which have been approved by the US Food and Drug Administration for the treatment of MDD since 1987 and have indications for a variety of mental health conditions, including anxiety, compulsions and eating disorders [81,82,83]