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AMSTAR 2 assessments indicate that the existing evidence is limited by methodological shortcomings, including incomplete reporting of excluded studies, suboptimal literature search strategies, and insufficient evaluation of how bias in primary studies may influence meta-analytic estimates

thus, it has a long half-life and strong biological activity

Y2H and GST pull-down assays showed that Pelo interacted with an E3 ubiquitin ligase, encoding a 658 amino acid protein that contained a C3HC4-type RING domain at its N-terminus (Fig

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Huh MS, Ivanochko D, Hashem LE, Curtin M, Delorme M, Goodall E, Yan K, Picketts DJ (2016) Stalled replication forks within heterochromatin require ATRX for protection