October 2017
doi:10.1016/j.archoralbio.2014.12.009 43
(4) within-group comparison of the change from baseline in blood chemistry (white blood cell count, red blood cell count, hematocrit, platelet count, prothrombin time, fasting plasma glucose, total cholesterol, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, creatinine, blood urea nitrogen, sodium, potassium, chloride, uric acid, total bilirubin, direct bilirubin, total protein, albumin, insulin, and C-peptide levels) and urinalysis (urinary albumin) after 52 weeks of intervention
Stability considerations Most reconstituted peptides remain stable for 3-4 weeks when refrigerated properly
Importantly, lixisenatide did not increase the risk of hospitalization for HF compared with placebo