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16 The observed association between GLP-1 receptor agonist use and reduced risk of legal blindness may be biologically plausible given their established anti-inflammatory and neuroprotective effects, including modulation of neuroinflammation and preservation of neuronal integrity

For example, a small pilot study might suggest benefits, but without larger, randomized controlled trials, these results are not reliable

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Each province conducts its own review through bodies like the Canadian Drug Expert Committee before adding medications to their formularies