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Patients with chronic kidney disease, cardiovascular diseases, and those with obesity related complications such as moderate to severe obstructive sleep apnea (OSA) should not use microdoses of GLP-1 medications

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The FDA enforcement discretion period ended in early spring of the prior year for state-licensed pharmacies, meaning compounding pharmacies now operate under stricter standard rules

The decision to continue, adjust, or discontinue semaglutide should be based on the overall risk-benefit assessment and whether a plausible connection between the medication and back pain can be established through clinical evaluation