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If fatigue remains problematic despite optimisation strategies, discuss with your healthcare provider whether Wegovy remains the most appropriate treatment option
It works through two mechanisms: inhibiting the enzyme tyrosinase (which is essential for melanin synthesis) and shifting the melanin production pathway from eumelanin (darker pigment) to pheomelanin (lighter pigment)
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It preserves regulatory feedback loops for safer hormone optimization
A 2023 analysis of the SUSTAIN and PIONEER trials published in Cardiovascular Diabetology showed significant reductions in high-sensitivity C-reactive protein, a marker of systemic inflammation, among patients taking semaglutide
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