This is supported by recent studies from US and German adults with T2D, which reported that the use of GLP-1RAs versus insulin resulted in lower emergency room visits and inpatient admissions but higher drug acquisition costs after treatment initiation [49, 50]
Some patients are able to sustain weight loss by making the healthy behaviors learned during treatment a permanent part of their lifestyle, while others may regain weight if they fail to adopt lasting changes
Whether a switch is safe depends on the cause of deficiency, symptoms, absorption, previous response, dose, adherence and follow-up
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High-frequency data collection, such as daily diaries, offers greater insight into patient experience but also introduces additional variability