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Patients considering GLP-1 therapy should inform their endocrinologist or primary care provider, as thyroid function monitoring may need to be intensified during periods of significant weight loss
The NTS is the main source of endogenous GLP-1 within the brain (Holt et al., 2019)
A 2023 review concluded that the widespread marketing of biotin for hair loss in healthy individuals is unsubstantiated biotin works best when genuine deficiency or health problems exist, not as cosmetic enhancement for people with adequate biotin levels
While Tirzepatide has not run a dedicated osteoarthritis trial, weight loss of any significant magnitude reliably reduces mechanical load on weight-bearing joints
1 More About Hormones and Headaches Neurological and endocrine studies have shown that estrogen seems to modulate the severity and frequency of migraines
