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Because of its extreme potencytargeting three receptors rather than one or twoit is not intended for "vanity" weight loss
2019 Jun 2;2019:4574276
The glucagon arm introduces a separate consideration: in non-diabetic research subjects, the insulinotropic GLP-1 effect generally offsets glucagon-driven hepatic glucose output, but rapid escalation can produce transient dysglycaemia
Given the significance of S -palmitoylation in cancer, the DHHCs and protein depalmitoylases are promising targets for cancer therapy
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