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[1] Cell Line:TRX2 -/- DT40 cells (chicken B-cell line) Concentration:1 mM Incubation Time:30 min pretreatment before 1 g/mL Doxycycline induction Result:Reduced activation of caspase-3 and caspase-9, key markers of mitochondrial apoptosis pathway, compared to untreated cells
J., Tilic, E
World J Hepatol 12(5):184206
Based on studies involving gene-targeted mice and cell culture experiments, the significance of AMP-activated protein kinase (AMPK), p21-activated kinase 2 (PAK2), cGMP-dependent protein kinase type I (cGKI), Janus kinase 3 (JAK3), mitogen and stress-activated protein kinase (MSK1/2), and phosphoinositide-dependent kinase 1 (PDK1) for eryptosis has been studied
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