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In addition, a further increase in NtGSTU1 expression at 3 and 6 h after virus inoculation was associated with enhanced HR-type resistance (i.e., significantly less necrotic lesions and reduced TMV-replication) in plants with a sufficient sulfate supply (Kirly et al., 2012)

When NAD+ levels drop, mitochondrial function suffers, energy production declines, and metabolism slows

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